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A 10- year-old child has been diagnosed with Juvenile diabetes mellitus (type 1 diabetes mellitus). This is a disorder of carbohydrate metabolism caused by insulin deficiency. The disease is often preceded by viral infection with inflammation of the beta cells of pancreas, but also exhibits genetic predisposition with a 40-50% concordance rate in monozygotic twins and clustering in families. Type 1 diabetes mellitus may be best described as a

A. Sex linked disorder

B. Congenital disorder

C. Sporadic disorder

D. Multifactorial disorder

E. Mendelian disorder

For details of the case, follow the link

http://usmle.biochemistryformedics.com/type-1-diabetes-mellitus-etiology/

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