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 Choose the correct Answer

1) Glucose is mainly absorbed by passive diffusion/ active transport.          

(Active transport)

2) GLUT-4 transporters are present in adipose tissues/red blood cells.       

(Adipose tissues  )

3) Insulin promotes Glycolysis/Glycogenolysis.                                         

(Glycolysis)

4) Lactase/ Lactate dehydrogenase is deficient in lactose intolerance.          

(Lactase)

5) In type 2 diabetes mellitus, the peripheral cells become oversensitive/ Insensitive to the effect of insulin.                                                                                 

(Insensitive)

6) Phosphorylase enzyme is active in the phosphorylated / dephosphorylated form.

(Phosphorylated)

7) Sorbitol is produced by the oxidation/reduction of glucose.                  

(Reduction)

8) Glucokinase/ Hexokinase can regulate the blood glucose level.              

(Glucokinase)

9) Chronic alcohol ingestion can produce hypoglycemia/hyperglycemia.

(Hypoglycemia)

10) Glucose-6- phosphatase / Glucose-6-phosphate dehydrogenase is deficient in Von- Gierke’s disease.                                            

(Glucose-6- phosphatase )

11) More the concentration of 2,3bisphosphoglycerate more/less will be the unloading of oxygen to the peripheral tissues.                                  

(More)

12) Glycated Hb is represented by HbAIa/HbAIc.                                     

(HbAIc.)

13) Ca ++ /Mg++   can activate phosphorylase kinase without phosphorylation.

( Ca ++)

14) Hypokalemia/Hyperkalemia is observed on treatment with insulin in diabetes mellitus.

(Hypokalemia)

15) Hypercholesterolemia/Hypocholesterolemia is observed in type 2 diabetes mellitus.

(Hypercholesterolemia     )

16) ATP and Citrate are negative/positive modifiers of PFK-I enzyme.

(Negative)

17) 51/53 amino acids are present in mature insulin.              

(51)

18) A low/ high ATP to ADP ratio is a stimulant for PDH kinase enzyme.

 (High)

19) Hexokinase/ Glucokinase enzyme is inhibited by feed back inhibition.        

(Hexokinase)

20) The preferred source of energy for the brain cells is glucose/ketone bodies.

(Glucose)

21) During overnight fasting blood glucose is maintained by Gluconeogenesis/ Glycogenolysis.                                                                                   

  (Glycogenolysis)

22) Transketolase/ Transaminase is TPP dependent.                               

(Transketolase    )

23) Free Glucose/ Glucose-1-phosphate is the end product of debranching enzyme catalyzed breakdown of glycogen.                                                     

(Free Glucose)

24) The half-life of Insulin is 5 minutes/5 hours.                                

(5 minutes)

25) Sorbitol dehydrogenase enzyme is absent in liver/ nerves.              

(Nerves)

26) 36 ATP/ 38 ATP molecules are produced by the complete oxidation of 1 molecule of glucose under aerobic conditions.                           

(38 ATP)

27) Malonate/ Oxamate is the inhibitor of Succinate dehydrogenase enzyme.

(Malonate)

28) The enzymes of TCA cycle are present in the mitochondria/ Cytoplasm.

 (Mitochondria)

29) Pyruvate/ Lactate is the end product of glycolysis under anaerobic conditions.

(Lactate)

30) No ATP/ 2 ATP when RL shunt is operating in the red blood cells.

(No ATP)

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5 Responses to Solution To Questions From Carbohydrate Metabolism (Choose The Correct Answer)

  • Sneha Desai says:

    Mam, for question 23, in glycogenolysis, isn't G-1-P the end product of debranching enzyme, which is then converted to G-6-P?

  • The product of debranching enzyme is Free glucose through its Amyloglucosidase component(At the branch point). G-1-P is the end product of phosphorylase catalyzed reaction, which is subsequently converted to G-6-P by phosphoglucomutase and finally to free glucose by glucose-6 phosphatase. Glucose-6 phosphatase is absent in muscles , free glucose is formed in liver only and that is poured in to circulation to maintain blood glucose conc.
    Hope dear, i am clear to you !
    Check your notes and see the figure to clarify your doubt.
    Namrata

  • Sneha Desai says:

    Okay. I think I see my mistake. Will check again in the notes and let you know. Thanks. :)

    In case I have any more doubts, will come to see you for sure. :)

  • Sneha Desai –> I think you have confused debranching enzyme with phosphorylase. Just compare the two enzymes and you will get your answer… The questions asks about debranching enzyme which has 2 components; the first one is involved in transfer of a trisaccharide. The second component is Amyloglucosidase (which is a hydrolase); it therefore releases FREE GLUCOSE and that is quite well stated in the notes. Hope this helps you clear your doubt.

  • Great, good concepts, Kavish, Keep it up.
    Namrata

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