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Solution To Questions From Carbohydrate Metabolism- State True or False
State true or false
1) Glyceraldehyde-3-phosphate dehydrogenase catalyzed step is the main step for energy yield under anaerobic conditions.
2) Succinate is the substrate for Succinate Thiokinase enzyme.
3) Glycerol kinase enzyme is absent in the adipose tissues.
4) Phosphoglycerate kinase catalyzed step yields energy by substrate level phosphorylation.
5) Diabetic ketoacidosis is a commonest complication of type 2 diabetes mellitus.
6) The plasma C- peptide level is a marker of endogenously synthesized insulin.
7) Insulin receptor has tyrosine kinase activity.
8) Acetyl co A is an ideal substrate for gluconeogenesis.
9) Insulin promotes lipolysis by stimulating hormone sensitive lipase.
10) Oral glucose tolerance test is a confirmatory test in suspected cases of diabetes mellitus.
11) Aconitase enzyme catalyzes the condensation of Acetyl co A and Oxalo acetate.
12) Enolase is inhibited by Arsenate.
13) Inherited Aldolase A and pyruvate kinase deficiencies in erythrocytes cause hemolytic anemia.
14) Muscle glycogen functions to store and export glucose to maintain blood glucose between meals.
15) Glucose 6-phosphatase hydrolyzes glucose 6-phosphate in muscles, yielding glucose that is exported, leading to an increase in the blood glucose concentration.
16) Liver and kidney are the major gluconeogenic tissues.
17) Galactose and fructose are readily converted to glucose in the liver.
18) Epinephrine and nor epinephrine stimulate the release of insulin.
( False )
19) Glucose 6-phosphate dehydrogenase is an NAD+dependent enzyme.
20) Ribose can not be synthesized in all tissues.
21) In the liver, fructose increases triacylglycerol synthesis and VLDL secretion, leading to hypertriacylglycerolemia.
( True )
22) Microalbuminuria is a measure of an early and reversible nephropathy.
( True )
23) A low blood glucose level is more harmful than hyperglycemia.
24) Hypoglycemia is not a diagnosis but is a biochemical sign associated with a group of diverse diseases.
25) A fall in pH stimulates phosphofructo kinase activity.
( False )
26) GLUT5, present in the small intestine, functions primarily as a fructose transporter.
( True )
27) Glycolysis is diminished and gluconeogenesis is accelerated in the fed state.
28) The formation of acetyl CoA from carbohydrates is less direct than from fat.
29) The rate of TCA cycle is reduced when the cell has a high level of ATP.
30) Two high-energy phosphate bonds are consumed in a reaction, which is catalyzed by pyruvate carboxylase.
( False )