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A 14-year-old high school girl who is extremely conscious about her appearance has gone a full day fasting to fit in to a dress she intentionally brought a size smaller than her actual size for a dance party. Which of the following organs/tissues contribute to the glucose that is being synthesized through gluconeogenesis during periods of prolonged fasting?

A. Spleen

B. Red blood cells

C. Skeletal muscle

D. Liver

E. Brain

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