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Membrane fluidity is required for the proper movement of erythrocytes through capillaries of the spleen. Patients with spur cell anemia have increased cholesterol content (> 40%) in the membranes of their erythrocytes, resulting in decreased membrane fluidity. Thus, erythrocytes from these patients are destroyed in the spleen.

Which of the following statements is incorrect concerning the significance of cholesterol?

A. Elevated levels of cholesterol are associated with atherosclerosis.

B. The serum total cholesterol content should be less than 200 mg/dl.

C. Cholesterol is a major component of gall stones.

D. Excess cholesterol is excreted from the liver in the bile as cholesterol or bile salts.

E. Cholesterol is a major precursor of fat soluble vitamins.

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