a) Phospholipase A2
b) Phospholipase C
c) Guanylate cyclase
Q.2- Phenylketonuria is characterized by-
a) Urine turning black on standing
b) Wolf like smell of urine
c) Mousy odor of urine
d) Smell of burnt sugar of urine
Q.3- The active form of Methionine is-
a) S- Acetyl methionine
b) S- Carboxyl methionine
c) S- Adenosyl methionine
d) N-acetyl methionine
Q.4- Patients with inherited defects of mitochondria involving components of the respiratory chain and oxidative phosphorylation present with all except-
b) Lactic acidosis
d) Mental retardation
Q.5- Which of the followings best describes the toxicity associated with Atractyloside
a) Acts as an inhibitor of ETC
b) Acts as an uncoupler
c) Acts as an inhibitor of ATP/ADP transporter
d) Inactivates ATP synthase complex
Q.6- A given substrate may be acted on by a number of different enzymes, each of which uses the same substrate(s) and produces the same product(s). The individual members of a set of enzymes sharing such characteristics are known as-
a) Group specific enzymes
c) Substarte specific enzymes
d) Allosteric enzymes
Q.7- Porphyrins are deposited in teeth and in bones. As a result, the teeth are reddish-brown and fluoresce on exposure to long-wave ultraviolet light, so-called ‘Erythrodontia ‘, is a sign of which porphyria?
a) Variegate porphyria
b) Acute intermittent porphyria
c) Congenital Erythropoietic porphyria
d) Hereditary Coproporphyria
Q.8- Which of the following reactions generates ATP-
a) Glucose to Glucose -6-phosphate
b) Pyruvate to Lactate
c) Phosphoenol pyruvate to Pyruvate
d) Glucose- 6-P to fructose-6 -P
Q.9- Formation of Galactose-1-P from Galactose is catalyzed by-
d) Galactose-1-P Uridyl transferase
Q.10-Which of the following is a cofactor in the reaction catalyzed by glyceraldehyde 3-phosphate dehydrogenase?
Q.11- Which out of the following enzymes is not TPP dependant?
a) PDH Complex
b) α- Keto glutarate dehydrogenase complex
c) Tryptophan pyrrolase
Q.12- Which out of the following amino acids carries a net positive charge at the physiological p H ?
d) None of the followings.
Q.13- All of the followings except one are coupling agents for the detoxification of Xenobiotics-
a) Glutamic acid
Q.14- Which out of the followings is produced as a result of detoxification by Glycine?
a) Mercapturic acid
b) Hippuric acid
c) Kynurenine acid
d) Xanthurenic acid
Q.15- Which of the following is a non reducing sugar?
Q.16- Which out of the followings is not an uncoupler of oxidative phosphorylation?
Q.17- Which out of the followings is not a product of tyrosine metabolism?
Q.18- Spot the inborn error whose early diagnosis is essential to avoid permanent brain damage?
b) Glycogen storage disease
d) Acute Intermittent Porphyria
Q.19-Down regulation of LDL receptor occurs due to-
a) Influx of cholesterol
b) Decreased activity of LCAT
c) Steroid synthesis
d) Bile acid synthesis
Q.20- Which of the following hormones promotes hypoglycemia?
b) Nor epinephrine
Key To Answers-
1)- c, 2)-c, 3)-c, 4)- d, 5)- c, 6)- b, 7)- c, 8)-c, 9)-d, 10)-d,11)-d,12)-d,13)-a, 14)-b,15)-b,16)-a,17)-b,18)-a, 19)-a,20)-d.
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