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One Word Answers

State true or false

1) The neonates treated by phototherapy for jaundice can develop riboflavin deficiency.                                  

2) Pantothenic acid deficiency affects fatty acid synthesis.           

3) Biotin is a sulfur containing vitamin.                             

4) Vitamin B12 can be stored in liver.    

5) Folic acid is required for the propagation of the nerve impulse. 

6) The patients treated by Isoniazid for tuberculosis can have pellagra like rashes on the body.                                                                     

7) The utilization of Tyrosine requires the presence of vitamin C.  

8) More the protein intake more is the requirement of Thiamine.

9) Niacin deficiency can precipitate B6 deficiency.    

10) Folic acid is a one carbon carrier in the body.                        

11) A pure vegetarian diet can produce vitamin B12 deficiency.

12) Pantothenic acid deficiency leads to fatty liver formation.       

13) Folic acid is a sulfur containing vitamin.   

14) Vitamin A is stored in the liver.      

15) Defective myelin sheath formation occurs in B12 deficiency.

16) The morning sickness of pregnancy can be treated by Vitamin B6.

17) L- Amino acid oxidases require the presence of vitamin C.

18) More the carbohydrate intake more is the requirement of Thiamine. 

19) Renal failure can precipitate vitamin D deficiency.      

20) Vitamin E is an antioxidant in the body.   

21) Isolated Riboflavin deficiency is not commonly encountered.  

22) Total non vegetarian diet can produce scurvy.

23) Pantothenic acid deficiency affects fatty acid degradation.     

24) Niacin can increase HDL levels  

25) Folic acid can be stored in the liver.

26) Thiamine is required for the propagation of the nerve impulses.

27) In addition to its coenzyme role, Riboflavin is the source of ADP-ribose for the ADP-ribosylation of proteins.                                

28) Some 60 mg of dietary niacin is equivalent to 1 mg of tryptophan.

29) Thiamine Nutritional Status Can Be Assessed by Erythrocyte Glutathione Reductase Activation.                                                           

30) The intestinal activity of carotene dioxygenase is fast, so that a negligible proportion of ingested beta -carotene may appear in the circulation unchanged.                                                

Key to answers

Q.A.- True or False

1)- (True)

2)- (True)

3)- (True)

4)-  (True)                             

5)-  (False)

6)- (True)       

7)-  (True)

8)- (False)

9)- (False)         

10)- (True)

11)- (True)

12)-  (True)

13)- (False)                   

14)- (True)                             

15)- (True)         

16)- (True)

17)- (False)

18)- (True)

19)- (True)          

20)- (True)                   

21)- (True)

22)- (True)                             

23)- (True)

24)- (True).                                      

25)- (False)                                      

26)- (True)

27)- (False) 

28)-  (False)

29)- (False)   

30)- (False)

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One word Answers

1)  Methyl Malonic aciduria is associated with vitamin B6/ B12 deficiency.

2) Glycogen synthesis/ degradation requires Vitamin B6.   

3) Carboxylation/ Decarboxylation reactions requires Biotin.  

4) In Vitamin B12 deficiency Folate is trapped in the demethylated/methylated form.                    

5) The coenzyme form of pyridoxine is Pyridoxal phosphate/Pyridoxol phosphate.        

6) Hydroxylation/ Dehydrogenation reactions require riboflavin. 

7) Pellagra is associated with deficiency of B1/ B3.

8) The Dehydro/ Hydroxylated form is the active form of ascorbic acid.

9) Methotrexate competitively inhibits synthesis of reduced form of Niacin/ Folic acid.                

10) Xanthurenic acid test is for the assessment of B6/ Folic acid deficiency

11)  Intrinsic factor is required for the absorption of vitamin B6/B12 

12) Menadione / Menaquinone is a synthetic form of vitamin K 

13) Carboxylation/ Decarboxylation reactions require B6.

14) The absorbable form of Thiamine is Free Thiamine/TPP 

15) Hydroxylation/ Dehydrogenation reactions require Ascorbic acid.

16) Pellagra is precipitated by the deficiency of B1/B6.  

17) The Dehydro/ Reduced form is the active form of Folic acid. 

18) Alcohol inhibits the absorption of Thiamine/vitamin A.  

19) Histidine loading test is for the assessment of B6/ Folic acid deficiency

20) Achlorhydria can cause vitamin B6/ B12 deficiency     

21) Heme synthesis/ degradation requires Vitamin B6   

22) Carboxylation of Glutamic acid residues requires vitamin K/Biotin during the process of coagulation.                                       

23) Reduction / Dehydrogenation reactions require NADPH  

24) Lactic acidosis is associated with deficiency of B1/ B3.   

25) “Burning feet syndrome” is a feature of niacin/Pantothenic acid deficiency.

26) Sulphonamides competitively inhibit synthesis of Niacin/Folic acid.

27) Retinol/ retinoic acid is required for the regulation of gene expression and tissue differentiation.

28) 11-cis Retinal/11-cis Retinol is required for vision.     

Q.B- Name the coenzyme for each of the following reactions-

1) Pyruvate——————————->Lactate.    

2) Pyruvate——————————–> Oxaloacetate.  

3) Pyruvate———————————>Alanine.    

4) Pyruvate———————————>Malate.  

5) Lysine————————————->Hydroxy Lysine. 

6) Glutamic acid————————->.Gamma Carboxy Glutamic acid  

7) Malate——————————–> Oxaloacetate.   

8) Glutamate——————————–>Alpha keto glutarate.  

9) Succinate——————————->Fumarate.   

10) Tyrosine——————————–>Tyramine.                                

11) Homocysteine————————> Methionine.  

12) L- Methyl Malonyl coA————> Succinyl co A.   

Key to answers

Q.A- Correct option

1) – B12

2) – Degradation      

3) – Carboxylation  

4) – Methylated 

5) – Pyridoxal phosphate                               

6)- Dehydrogenation   

7) – B3            

8) – Dehydro

9) – Folic acid   

10) – B6 deficiency

11) – B12

12) – Menadione

13) – Decarboxylation    

14) – Free Thiamine    

15) – Hydroxylation         

16) – B6     

17) – Reduced

18) – Thiamine      

19) -B6

20) – B12      

21) – Synthesis             

22) – Vitamin K

23) – Reduction  

24) – B1  

25)- Pantothenic acid

26)- Folic acid

27)- Retinoic acid

28)- 11-cis Retinal       

Q.B- Coenzyme for each reaction

1) – Niacin-NAD+

2) – Biotin                                 

3) – Pyridoxal phosphate-B6P             

4) –  Niacin-NADP+                                                  

5) – Vitamin C                               

6) – Vitamin K  

7)- Niacin-NAD+

8) – NAD+ or NADP+  

9)- Riboflavin-FAD                                    

10) -Pyridoxal phosphate-B6 P 

11)- Vitamin B12 and Folic acid                                   

12)-  Vitamin B12      

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