Main Menu

Advertisement

One Word Answers

State true or false

1) Glyceraldehyde-3-phosphate dehydrogenase catalyzed step is the main step for energy yield under anaerobic conditions.                                   

(False)        

2) Succinate is the substrate for Succinate Thiokinase enzyme.    

(False)

3) Glycerol kinase enzyme is absent in the adipose tissues.          

(True)

4) Phosphoglycerate kinase catalyzed step yields energy by substrate level phosphorylation.                                                                       

(True)

5) Diabetic ketoacidosis is a commonest complication of type 2 diabetes mellitus.

(False)

6) The plasma C- peptide level is a marker of endogenously synthesized insulin.

(True)

7)  Insulin receptor has tyrosine kinase activity.                            

(True)

8) Acetyl co A is an ideal substrate for gluconeogenesis.              

(False)

9) Insulin promotes lipolysis by stimulating hormone sensitive lipase.

(False)

10) Oral glucose tolerance test is a confirmatory test in suspected cases of diabetes mellitus.                                                                                   

(True)

11) Aconitase enzyme catalyzes the condensation of Acetyl co A and Oxalo acetate.

(False)

12) Enolase is inhibited by Arsenate.                                          

(False)

13) Inherited Aldolase A and pyruvate kinase deficiencies in erythrocytes cause hemolytic anemia.                                                                   

(True)

14) Muscle glycogen functions to store and export glucose to maintain blood glucose between meals.                                                                        

(False)

15) Glucose 6-phosphatase hydrolyzes glucose 6-phosphate in muscles, yielding glucose that is exported, leading to an increase in the blood glucose concentration.                                                                                                     

(False)

16) Liver and kidney are the major gluconeogenic tissues.           

(True)

17) Galactose and fructose are readily converted to glucose in the liver. 

(True)        

18) Epinephrine and nor epinephrine stimulate the release of insulin.

( False )

19) Glucose 6-phosphate dehydrogenase is an NAD+dependent enzyme.

( False)

20) Ribose can not be synthesized in all tissues.                          

( False)

21) In the liver, fructose increases triacylglycerol synthesis and VLDL secretion, leading to hypertriacylglycerolemia.                                                                                                                                                           

(   True )

22) Microalbuminuria is a measure of an early and reversible nephropathy.

(   True     )

23) A low blood glucose level is more harmful than hyperglycemia.    
( True)

24) Hypoglycemia is not a diagnosis but is a biochemical sign associated with a group of diverse diseases.                                                                      

( True)

25) A fall in pH stimulates phosphofructo kinase activity.            

( False )

26) GLUT5, present in the small intestine, functions primarily as a fructose transporter.

( True  )

27) Glycolysis is diminished and gluconeogenesis is accelerated in the fed state.

( False)

28) The formation of acetyl CoA from carbohydrates is less direct than from fat.

(True )

29) The rate of TCA cycle is reduced when the cell has a high level of ATP.

(True )

30) Two high-energy phosphate bonds are consumed in a reaction, which is catalyzed by pyruvate carboxylase.                                                                                                                                                                    

( False )

 

Please help "Biochemistry for Medics" by CLICKING ON THE ADVERTISEMENTS above!

 Choose the correct Answer

1) Glucose is mainly absorbed by passive diffusion/ active transport.          

(Active transport)

2) GLUT-4 transporters are present in adipose tissues/red blood cells.       

(Adipose tissues  )

3) Insulin promotes Glycolysis/Glycogenolysis.                                         

(Glycolysis)

4) Lactase/ Lactate dehydrogenase is deficient in lactose intolerance.          

(Lactase)

5) In type 2 diabetes mellitus, the peripheral cells become oversensitive/ Insensitive to the effect of insulin.                                                                                 

(Insensitive)

6) Phosphorylase enzyme is active in the phosphorylated / dephosphorylated form.

(Phosphorylated)

7) Sorbitol is produced by the oxidation/reduction of glucose.                  

(Reduction)

8) Glucokinase/ Hexokinase can regulate the blood glucose level.              

(Glucokinase)

9) Chronic alcohol ingestion can produce hypoglycemia/hyperglycemia.

(Hypoglycemia)

10) Glucose-6- phosphatase / Glucose-6-phosphate dehydrogenase is deficient in Von- Gierke’s disease.                                            

(Glucose-6- phosphatase )

11) More the concentration of 2,3bisphosphoglycerate more/less will be the unloading of oxygen to the peripheral tissues.                                  

(More)

12) Glycated Hb is represented by HbAIa/HbAIc.                                     

(HbAIc.)

13) Ca ++ /Mg++   can activate phosphorylase kinase without phosphorylation.

( Ca ++)

14) Hypokalemia/Hyperkalemia is observed on treatment with insulin in diabetes mellitus.

(Hypokalemia)

15) Hypercholesterolemia/Hypocholesterolemia is observed in type 2 diabetes mellitus.

(Hypercholesterolemia     )

16) ATP and Citrate are negative/positive modifiers of PFK-I enzyme.

(Negative)

17) 51/53 amino acids are present in mature insulin.              

(51)

18) A low/ high ATP to ADP ratio is a stimulant for PDH kinase enzyme.

 (High)

19) Hexokinase/ Glucokinase enzyme is inhibited by feed back inhibition.        

(Hexokinase)

20) The preferred source of energy for the brain cells is glucose/ketone bodies.

(Glucose)

21) During overnight fasting blood glucose is maintained by Gluconeogenesis/ Glycogenolysis.                                                                                   

  (Glycogenolysis)

22) Transketolase/ Transaminase is TPP dependent.                               

(Transketolase    )

23) Free Glucose/ Glucose-1-phosphate is the end product of debranching enzyme catalyzed breakdown of glycogen.                                                     

(Free Glucose)

24) The half-life of Insulin is 5 minutes/5 hours.                                

(5 minutes)

25) Sorbitol dehydrogenase enzyme is absent in liver/ nerves.              

(Nerves)

26) 36 ATP/ 38 ATP molecules are produced by the complete oxidation of 1 molecule of glucose under aerobic conditions.                           

(38 ATP)

27) Malonate/ Oxamate is the inhibitor of Succinate dehydrogenase enzyme.

(Malonate)

28) The enzymes of TCA cycle are present in the mitochondria/ Cytoplasm.

 (Mitochondria)

29) Pyruvate/ Lactate is the end product of glycolysis under anaerobic conditions.

(Lactate)

30) No ATP/ 2 ATP when RL shunt is operating in the red blood cells.

(No ATP)

Please help "Biochemistry for Medics" by CLICKING ON THE ADVERTISEMENTS above!

State true or false

1) Glyceraldehyde-3-phosphate dehydrogenase catalyzed step is the main step for energy yield under anaerobic conditions.

2) Succinate is the substrate for Succinate Thiokinase enzyme.

3) Glycerol kinase enzyme is absent in the adipose tissues.

4) Phosphoglycerate kinase catalyzed step yields energy by substrate level phosphorylation.

5) Diabetic ketoacidosis is a commonest complication of type 2 diabetes mellitus.

6) The plasma C- peptide level is a marker of endogenously synthesized insulin.

7) Insulin receptor has tyrosine kinase activity.

8) Acetyl co A is an ideal substrate for gluconeogenesis.

9) Insulin promotes lipolysis by stimulating hormone sensitive lipase.

10) Oral glucose tolerance test is a confirmatory test in suspected cases of diabetes mellitus.

11) Aconitase enzyme catalyzes the condensation of Acetyl co A and Oxalo acetate.

12) Enolase is inhibited by Arsenate.

13) Inherited Aldolase A deficiency and pyruvate kinase deficiency in erythrocytes cause hemolytic anemia.

14) Muscle glycogen functions to store and export glucose to maintain blood glucose between meals.

15) Glucose 6-phosphatase hydrolyzes glucose 6-phosphate in muscles, yielding glucose that is exported, leading to an increase in the blood glucose concentration.

16) Liver and kidney are the major gluconeogenic tissues.

17) Galactose and fructose are readily converted to glucose in the liver.

18) Epinephrine and nor epinephrine stimulate the release of insulin.

19) Glucose 6-phosphate dehydrogenase is an NAD+-dependent enzyme.

20) Ribose can not be synthesized in all tissues.

21) In the liver, fructose increases triacylglycerol synthesis and VLDL secretion, leading to hypertriacylglycerolemia.

22) Microalbuminuria is a measure of a nearly and reversible nephropathy.

23) A low blood glucose level is more harmful than hyperglycemia.

24) Hypoglycemia is not a diagnosis but is a biochemical sign associated with a group of diverse diseases.

25) A fall in pH stimulates phosphofructo kinase activity.

26) GLUT5, present in the small intestine, functions primarily as a fructose transporter.

27) Glycolysis is diminished and gluconeogenesis is accelerated in the fed state.

28) The formation of acetyl CoA from carbohydrates is less direct than from fat.

29) The rate of TCA cycle is reduced when the cell has a high level of ATP.

30) Two high-energy phosphate bonds are consumed in a reaction, which is catalyzed by pyruvate carboxylase.

 

Please help "Biochemistry for Medics" by CLICKING ON THE ADVERTISEMENTS above!

Choose the correct Answer

1) Glucose is mainly absorbed by passive diffusion/ active transport.

2) GLUT-4 transporters are present in adipose tissues/red blood cells.

3) Insulin promotes Glycolysis/Glycogenolysis.

4) Lactase/ Lactate dehydrogenase is deficient in lactose intolerance.

5) In type 2 diabetes mellitus, the peripheral cells become oversensitive/ Insensitive to the effect of insulin.

6) Phosphorylase enzyme is active in the phosphorylated / dephosphorylated form.

7) Sorbitol is produced by the oxidation/reduction of glucose.

8) Glucokinase/ Hexokinase can regulate the blood glucose level.

9) Chronic alcohol ingestion can produce hypoglycemia/hyperglycemia.

10) Glucose-6- phosphatase / Glucose-6-phosphate dehydrogenase is deficient in Von- Gierke’s disease.

11) More the concentration of 2,3bisphosphoglycerate more/less will be the unloading of oxygen to the peripheral tissues.

12) Glycated Hb is represented by HbAIa/HbAIc.

13) Ca ++ /Mg++   can activate phosphorylase kinase without phosphorylation.

14) Hypokalemia/Hyperkalemia is observed on treatment with insulin in diabetes mellitus.

15) Hypercholesterolemia/Hypocholesterolemia is observed in type 2 diabetes mellitus.

16) ATP and Citrate are negative/positive modifiers of PFK-I enzyme.

17) 51/53 amino acids are present in mature insulin.

18) A low/ high ATP to ADP ratio is a stimulant for PDH kinase enzyme.

19) Hexokinase/ Glucokinase enzyme is inhibited by feed back inhibition.

20) The preferred source of energy for the brain cells is glucose/ketone bodies.

21) During overnight fasting blood glucose is maintained by Gluconeogenesis/ Glycogenolysis.

22) Transketolase/ Transaminase is TPP dependent.

23) Free Glucose/ Glucose-1-phosphate is the end product of debranching enzyme catalyzed breakdown of glycogen.

24) The half-life of Insulin is 5 minutes/5 hours.

25) Sorbitol dehydrogenase enzyme is absent in liver/ nerves.

26) 36 ATP/ 38 ATP molecules are produced by the complete oxidation of 1 molecule of glucose under aerobic conditions.

27) Malonate/ Oxamate is the inhibitor of Succinate dehydrogenase enzyme. 28) The enzymes of TCA cycle are present in the mitochondria/ Cytoplasm.

29) Pyruvate/ Lactate is the end product of glycolysis under anaerobic condition

30) No ATP/ 2 ATP when RL shunt is operating in the red blood cells.

Please help "Biochemistry for Medics" by CLICKING ON THE ADVERTISEMENTS above!

Advertisement