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A new-born becomes progressively lethargic after feeding. His respiratory rate increases and he becomes virtually comatose, responding only to painful stimuli, and exhibits mild respiratory alkalosis. Suspicion of a urea cycle disorder is aroused and evaluation of serum amino acid levels is initiated. In the presence of hyperammonemia, production of which of the following amino acids is always increased?

A. Glycine

B. Arginine

C. Proline

D. Histidine

E. Glutamine

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