A 23-year-old body builder visits his physician with complaints of fatigue, depression, insomnia, hair loss and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency given the patients’ diet and symptoms. Which of the following is biotin required for?
A. The formation of cis-retinal
B. Transfer of 1-carbon units
C. Hydroxylation reactions
D. Carboxylation of pyruvate
E. Decarboxylation of α-Keto acids
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