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Case details

An 8-year-old girl presents with precocious puberty, short stature, and coffee-colored macules. The patient has been diagnosed with McCune-Albright syndrome that results from estrogen production due to excessive Aromatase activity from ovarian follicular cysts. To treat the precocious puberty and other symptoms, the patient has been prescribed with a drug that inhibits the Aromatase activity. The drug is known to act by binding to substrate binding site, producing an increase in km.

Which of the following choices best describes the mechanism of inhibition of the drug?

A. Competitive

B. Non Competitive

C. Allosteric

D. Suicidal

E. Feedback inhibition

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